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Food Intake Regulation, Obesity, Cardiovascular Disease, Metabolic Disorders, Polyphenols
Appetite regulation and vascular / metabolic disease: Research in appetite regulation emphasizes the effects of bioactive food components on mechanistic and behavioral processes of food intake and body weight regulation. Properties of fibers, micro- and macro-molecule interactions, and food matrix effects in the gut to alter metabolic and endocrine systems that impact feeding behavior are a primary focus. Vascular and metabolic research emphasizes dietary attributes contributing to and preventing atherosclerotic disease, diabetes and related metabolic dysregulation. Plant bioactives, specifically flavonoids, on disease risk endpoints are of particular interest, including bioavailability, pharmacokinetics and the relationship to endothelium function, platelet activation, insulin and glucose metabolism, inflammatory and oxidative stress responses during acute and chronic interventions. The research approach includes human and basic science methodology.
2014 Excellence in Teaching Award- School of Applied Technology / Institute for Food Safety and Health
2008 Excellence in Research and High Performance award- Directors award, National Center for Food Safety and Technology
2012 to present: Editor-in-Chief, Nutrition and Aging, IOS Press
National and International Committee Panels
The Obesity Society - Planning committee, annual meeting
American Chemical Society, Agriculture and Food Research Division- Chair Nutritional Chemistry
Dannon Leadership Institute, Alumni Association member
Berry Health Benefits Symposium –Planning committee annual meeting; Session Chair, Heart Health; Panel Organizer and Chair, Creating trends: Using Health Research to Create Trends
American Society for Nutrition
The Obesity Society
Institute of Food Technologist
Phi Tau Sigma
Selected publications. For more complete listing search PubMed
1. Joseph S, Edirisinghe I, Burton-Freeman B*. Fruit polyphenols: a review of anti-inflammatory effects in humans. Critical Rev in Food Sci and Nutrition, 2013 In Press.
2. Banaszewski K, Park E, Edirisinghe I, Cappozzo J, Burton-Freeman B*. A pilot study to investigate bioavailability of strawberry anthocyanins and characterize postprandial plasma polyphenols by Q-TOF LC/MS in humans. J Berry Res, 2013 3:113-126.
3. Tadapaneni RK, Banaszewski K, Patazca E, Edirisinghe I, Cappozzo J, Jackson L, Burton-Freeman B*. Effect of High-Pressure Processing and Milk on the Anthocyanin Composition and Antioxidant Capacity of Strawberry-Based Beverages. J Agric Food Chem. 2012 Jan 17 [Epub ahead of print].
4. Edirisinghe I, Banaszewski K, Cappozzo J, McCarthy D, Burton-Freeman BM*. Effect of Blackcurrant Anthocyanins on the Activation of eNOS in-vitro in Human Endothelial Cells. J Agric Food Chem. 2011 Aug 24;59(16):8616-24..
5. Ellis CL, Edirisinghe I, Kappagoda T, Burton-Freeman, B*. Attenuation of meal-induced inflammatory and thrombotic responses in overweight men and women after 6-week daily strawberry (Fragaria) intake: A randomized placebo-controlled trial. J Atheroscler Thromb. 2011, 18(4):318-27.
6. Burton-Freeman B*. and Reimers K. Tomato Consumption and Health: Emerging Benefits. Am J Lifestyle Medicine. 2010 Nov 19, doi:10.1177/1559827610387488.
7. Burton-Freeman B*. Postprandial metabolic events and fruit derived phenolics: A review of the science. Br. J. Nutr. 2010 Oct;104 Suppl 3:S1-14. Review. (IF:3.3)
8. Burton-Freeman B*, Linares A, Hyson D, Kappagoda CT. Strawberry modulates LDL oxidation and postprandial lipemia in response to high fat meal in overweight hyperlipidemic men and women. J Am Coll Nutr. 2010 29(1):46-54.
9. Lewis K and Burton-Freeman B*. The role of innovation and technology in meeting individual nutritional needs. J. Nutr. 2010 Feb;140(2):426S-36S.
10. Burton-Freeman B and Keim, N. Glycemic index, cholecystokinin (CCK), satiety and disinhibition: Is there an unappreciated paradox for overweight women? Int J Obes (Lond). 2008 Nov;32(11):1647-54.
11. Burton-Freeman B*. Glycomacropeptide (GMP) is not critical to whey-induced satiety, but may have a unique role in energy regulation through cholecystokinin (CCK). Physiology and Behavior. 2008 Jan 28;93(1-2):379-87.
12. Burton-Freeman B*. Sex and cognitive dietary restraint influence cholecystokinin release and satiety in response to preloads varying in fatty acid composition and content. J. Nutr 2005 135(6): 1407-1414. 2005.
13. Burton-Freeman B*, Davis P, Schneeman B. The interaction of fat availability and sex in mixed-food meals on postprandial satiety. Am. J. Clin. Nutr. 2004 80(5): 1207-1215.
14. Burton-Freeman B, Davis P, Schneeman B*. Plasma Cholecystokinin is associated with subjective measures of satiety in women. Am. J. Clin. Nutr. 2002 76 (3): 659-667.
15. Burton-Freeman B*. Dietary Fiber and Energy Regulation. J. Nutr. 2002 130: 272s-275s. (IF: 4.196)
16. Burton-Freeman B*, Gietzen D, Schneeman B. The role of cholecystokinin (CCK) and serotonin (5-HT3) receptors in the regulation of fat-induced satiety. Am. J. Physiol. 1999 276: R429-R434. (IF: 3.622)